本頁只刊出中文翻譯與中文說明；英文原文請見下方原文連結。
原文連結
論文資訊
- 類型：已發表論文
- 日期：2016-02-19
摘要
Kinetochores allow attachment of chromosomes to spindle microtubules. Moreover, they host 蛋白質s that permit correction of erroneous attachments and prevent premature anaphase onset before bi-orientation of all chromosomes in metaphase has been achieved. Kinetochores are assembled from subcomplexes. Kinetochore 蛋白質s as well as the underlying centromere 蛋白質s and the centromeric DNA sequences evolve rapidly despite their fundamental importance for faithful chromosome segregation during mitotic and meiotic divisions. During 演化 of Drosophila melanogaster, several centromere 蛋白質s were lost and a recent gene duplication has resulted in two Nnf1 paralogs, Nnf1a and Nnf1b, which code for alternative forms of a Mis12 kinetochore complex component. The rapid 演化ary divergence of centromere/ kinetochore
※ 此為已發表論文，全文需透過期刊付費取得