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原文連結
論文資訊
- 類型：已發表論文
- 日期：2016-02-24
摘要
Background: The accurate annotation of genes in newly sequenced 基因組s remains a challenge. Although sophisticated comparative pipelines are available, 計算ly derived gene models are often less than perfect. This is particularly true when multiple similar paralogs are present. The issue is aggravated further when 基因組s are assembled only at a preliminary draft level to contigs or short scaffolds. However, these 基因組s deliver valuable 資訊 for studying gene families. High accuracy models of 蛋白質 coding genes are needed in particular for 系統發育s and for the analysis of gene family histories. Results: We present a pipeline, ExonMatchSolver, that is designed to help the user to produce and curate high quality models of the 蛋白質-coding part of genes. The tool in particular tackles the problem of identifyin
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