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原文連結
論文資訊
- 類型：已發表論文
- 日期：2016-03-28
摘要
IMPORTANCE Current acellular pertussis vaccinesmay not protect against 傳播 of Bordetella pertussis. OBJECTIVE To assess whether a priming dose of whole-cell pertussis (wP) vaccine is cost-effective at reducing pertussis infection in infants. DESIGN, SETTING, AND PARTICIPANTS 數學 model of pertussis 傳播 fit to US incidence data in a simulation of the US 族群. In this simulation study conducted from June 2014 to May 2015, the 族群 was divided into 9 age groups corresponding to the current pertussis 疫苗接種 schedule and fit to 2012 pertussis incidence. INTERVENTIONS Inclusion of a priming dose of wP vaccine into the current acellular pertussis 疫苗接種 schedule. MAIN OUTCOMES AND MEASURES Reductions in symptomatic pertussis incidence by age group, increases in wP vaccine-related adverse effects, and quality
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