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原文連結
論文資訊
- 類型：已發表論文
- 日期：2016-04-01
摘要
The rise of multicellularity in the early 演化 of life represents a major challenge for 演化ary biology. Guidance for finding answers has emerged from disparate fields, from 系統發育s to modelling and synthetic biology, but little is known about the potential origins of multicellular aggregates before 遺傳 programmes took full control of developmental processes. Such aggregates should involve spatial organization of differentiated cells and the modification of flows and concentrations of metabolites within well-defined boundaries. Here, we show that, in an environment where limited nutrients and toxic metabolites are introduced, a 族群 of cells capable of 隨機 differentiation and differential adhesion can develop into multicellular aggregates with conflict mediation mechanisms and a complex internal str
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