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原文連結
論文資訊
- 類型：已發表論文
- 日期：2016-05-11
摘要
Experiments have found that the growth rate and certain other macroscopic properties of 細菌l cells in steady-state cultures depend upon the medium in a surprisingly simple manner; these dependencies are referred to as 'growth laws'. Here we construct a dynamical model of interacting intracellular 族群s to understand some of the growth laws. The model has only three 族群 variables: an amino acid pool, a pool of enzymes that transport an external nutrient and produce the amino acids, and ribosomes that catalyze their own and the enzymes' production from the amino acids. We assume that the cell allocates its resources between the enzyme sector and the ribosomal sector to maximize its growth rate. We show that the empirical growth laws follow from this assumption and derive analytic expressions for
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