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論文資訊
- 類型：已發表論文
- 日期：2016-09-01
摘要
Adaptive 適應度景觀s are a fundamental concept in 演化ary biology that relate the genotypes of individuals to their fitness. In the end, the 演化ary fate of evolving 族群s depends on the topography of the landscape, that is, the numbers of accessible 突變al pathways and possible fitness peaks (i.e., adaptive solutions). For a long time, 適應度景觀s were only theoretical constructions due to a lack of precise 資訊 on the mapping between genotypes and phenotypes. In recent years, however, efforts have been devoted to characterizing the properties of empirical 適應度景觀s for individual 蛋白質s or for microbes adapting to artificial environments. In a previous study, we characterized the properties of the empirical 適應度景觀 defined by the first five 突變s fixed during 適應 of tobacco etch poty病毒 (TEV) to a new experimental hos
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