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原文連結
論文資訊
- 類型：已發表論文
- 日期：2016-12-19
摘要
Horizontal gene transfer (HGT) is pervasive in 病毒es and thought to be a key mechanism in their 演化. On the other hand, strong selective constraints against increasing 基因組 size are an impediment for HGT, rapidly purging horizontally transferred sequences and thereby potentially hindering 演化ary innovation. Here, we explore experimentally the 演化ary fate of 病毒es with simulated HGT events, using the plant RNA 病毒 Tobacco etch 病毒 (TEV), by separately introducing two functional, exogenous sequences to its 基因組. One of the events simulates the acquisition of a new function though HGT of a conserved AlkB domain, responsible for the repair of alkylation or methylation damage in many organisms. The other event simulates the acquisition of a sequence that duplicates an existing function, through HGT of t
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