聖塔非研究所

摘要 Existing theory on competition for hosts between

2017-05-01 · 已發表論文 · 更新 2026/08/30 下午12:48

摘要 Existing theory on competition for hosts between pathogen strains has proposed that 免疫 selection can lead to the maintenance of strain structure consisting of discrete, weakly overlapping…

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論文資訊

  • 類型:已發表論文
  • 日期:2017-05-01

摘要

Existing theory on competition for hosts between pathogen strains has proposed that 免疫 selection can lead to the maintenance of strain structure consisting of discrete, weakly overlapping antigenic repertoires. This prediction of strain theory has conceptual overlap with fundamental ideas in 生態學 on niche partitioning and limiting similarity between coexisting 物種 in an ecosystem, which oppose the hypothesis of neutral coexistence. For Plasmodium falciparum, strain theory has been specifically proposed in relation to the major surface antigen of the blood stage, known as PfEMP1 and encoded by the multicopy multigene family known as the var genes. Deep sampling of the DBLa domain of var genes in the local 族群 of Bakoumba, West Africa, was completed to define whether patterns of repertoire over

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