本頁只刊出中文翻譯與中文說明；英文原文請見下方原文連結。
原文連結
論文資訊
- 類型：已發表論文
- 日期：2017-06-08
摘要
RNA 病毒es are one of the fastest-evolving 生物 entities. Within their hosts, they exist as 遺傳ally diverse 族群s (i.e., viral mutant 群集s), which are sculpted by different 演化ary mechanisms, such as 突變, 自然選擇, and 遺傳漂變, and also the interactions between 遺傳 variants within the mutant 群集s. To elucidate the mechanisms that modulate the 族群 多樣性 of an important plant-pathogenic 病毒, we performed 演化 experiments with Potato 病毒 Y (PVY) in potato genotypes that differ in their defense response against the 病毒. Using deep sequencing of small RNAs, we followed the temporal dynamics of standing and newly generated variations in the evolving viral lineages. A time-sampled approach allowed us to (i) reconstruct theoretical haplo-types in the starting 族群 by using clustering of single nucleotide polymorphisms' trajec
※ 此為已發表論文，全文需透過期刊付費取得