聖塔非研究所

摘要 Determining the fitness of viral genotypes has be

2018-03-08 · 已發表論文 · 更新 2026/08/30 下午12:48

摘要 Determining the fitness of viral genotypes has become a standard practice in virology as it is essential to evaluate their 演化ary potential. Darwinian fitness, defined as the advantage of …

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  • 類型:已發表論文
  • 日期:2018-03-08

摘要

Determining the fitness of viral genotypes has become a standard practice in virology as it is essential to evaluate their 演化ary potential. Darwinian fitness, defined as the advantage of a given genotype with respect to a reference one, is a complex property that captures, in a single figure, differences in performance at every stage of viral infection. To what extent does viral fitness result from specific molecular interactions with host factors and regulatory 網絡s during infection? Can we identify host genes in functional classes whose expression depends on viral fitness? Here, we compared the transcriptomes of tobacco plants infected with seven genotypes of tobacco etch poty病毒 that differ in fitness. We found that the larger the fitness differences among genotypes, the more dissimilar t

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