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論文資訊
- 類型:已發表論文
- 日期:2018-06-04
摘要
Phages, the 病毒es of 細菌, have been proposed as anti細菌l 智能體s to complement or replace 抗生素s due to the growing problem of resistance. In nature and in the clinic, 抗生素s are ubiquitous and may affect phages indirectly via impacts on 細菌l hosts. Even if the synergistic association of phages and 抗生素s has been shown in several studies, the focus is often on 細菌 with little known about the impact on phages. 演化ary studies have demonstrated that time scale is an important factor in understanding the consequences of antimicrobial strategies, but this perspective is generally overlooked in phage-抗生素 combination studies. Here, we explore the effects of 抗生素s on phages targeting the opportunistic pathogen Pseudomonas aeruginosa. We go beyond previous studies by testing the interaction between several types
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