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原文連結
論文資訊
- 類型：已發表論文
- 日期：2018-07-16
摘要
Background: Most 系統發育 studies using molecular data treat gaps in multiple sequence alignments as missing data or even completely exclude alignment columns that contain gaps. Results: Here we show that gap patterns in large-scale, 基因組-wide alignments are themselves 系統發育ally informative and can be used to infer reliable phylogenies provided the gap data are properly filtered to reduce noise introduced by the alignment method. We introduce here the notion of split-inducing indels (splids) that define an approximate bipartition of the taxon set. We show both in simulated data and in case studies on real-life data that splids can be efficiently extracted from phylogenomic data sets. Conclusions: Suitably processed gap patterns extracted from 基因組-wide alignment provide a surprisingly clear 系統發育
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