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論文資訊
- 類型：已發表論文
- 日期：2018-08-20
摘要
Introduction: The prospect that we may be able to predict the outcome of future 演化ary processes has motivated recent investigations of the factors that determine this predictability (Lässig et al. 2017). At first sight, predicting 演化 may seem an unsurmountable goal, and perhaps even naïve, given the many 隨機 factors involved, prominently among them environmental change and the origin of new heritable variants. Yet, the situation is not entirely hopeless, as we can predict general features of 演化, such as the dynamics of 適應 resulting from available 遺傳 variation (Fisher 1930), and the rate of 基因組 演化 in the absence of selection (Kimura 1968). A particularly complicating factor, realized long ago by Sewall Wright (Wright 1932), is that the fitness consequences of 突變s may vary in an unpredictable
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