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原文連結
論文資訊
- 類型：已發表論文
- 日期：2019-12-13
摘要
Focal to bilateral tonic-clonic seizures are associated with lower quality of life, higher risk of seizure-related injuries, increased chance of sudden unexpected death, and unfavourable treatment outcomes. Achieving greater understanding of their underlying circuitry offers better opportunity to control these seizures. Towards this goal, we provide a 網絡 science perspective of the interactive pathways among basal ganglia, thalamus and cortex, to explore the imprinting of secondary seizure generalization on the mesoscale 大腦 網絡 in temporal lobe epilepsy. Specifically, we parameterized the functional organization of both the thalamocortical 網絡 and the basal ganglia-thalamus 網絡 with resting state functional Mill in three groups of patients with different focal to bilateral tonic-clonic seizure
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