摘要 It has long been suspected that living systems op

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論文資訊

• 類型：已發表論文
• 日期：2020

摘要

It has long been suspected that living systems operate out of 熱力學 equilibrium1, consuming energy and producing 熵 in the environment in order to perform 生物 functions. Recent efforts at the microscale have established that non-equilibrium processes are critical for molecular and cellular operations2–8. However, it remains unclear whether non-equilibrium dynamics manifest at macroscopic scales, and if so, how such dynamics support higher-order 生物 functions. Here we present a framework to probe for non- equilibrium processes by quantifying 熵 production in macroscopic systems. We apply our method to the human 大腦, an organ whose immense metabolic consumption drives a diverse range of 認知 functions9,10. Using whole-大腦 imaging data, we demonstrate that the 大腦 fundamentally operates out of equilibri

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