本頁只刊出中文翻譯與中文說明；英文原文請見下方原文連結。
原文連結
論文資訊
- 類型：已發表論文
- 日期：2020-08-13
摘要
We study the genotype-phenotype maps of 80 quantitative phenotypes in the model plant Arabidopsis thaliana, by representing the genotypes affecting each phenotype as a genotype 網絡. In such a 網絡, each vertex or node corresponds to an individual's genotype at all those genomic loci that affect a given phenotype. Two vertices are connected by an edge if the associated genotypes differ in exactly one nucleotide. The 80 genotype 網絡s we analyze are based on data from 基因組-wide association studies of 199A.thalianaaccessions. They form connected graphs whose topography differs substantially among phenotypes. We focus our analysis on the incidence of epistasis (non-additive interactions among 突變s) because a high incidence of epistasis can reduce the accessibility of 演化ary paths towards high or low p
※ 此為已發表論文，全文需透過期刊付費取得