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原文連結
論文資訊
- 類型：已發表論文
- 日期：2020-12-10
摘要
A promising, yet still under development approach to 癌症 treatment is based on the idea of differentiation therapy (DTH). Most tumours are characterized by poorly differentiated cell 族群s exhibiting a marked loss of traits associated to communication and tissue homeostasis. DTH has been suggested as an alternative (or complement) to cytotoxic-based approaches, and has proven successful in some specific types of 癌症 such as acute promyelocytic leukemia (APL). While novel drugs favouring the activation of differentiation therapies are being tested, several open problems emerge in relation to its effectiveness on solid tumors. Here we present a 數學 framework to DTH based on a well-known ecological model used to describe habitat loss. The models presented here account for some of the observed clin
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