本頁只刊出中文翻譯與中文說明；英文原文請見下方原文連結。
原文連結
論文資訊
- 類型：已發表論文
- 日期：2021-04-01
摘要
We study a simplified model of gene regulatory 網絡 演化 in which links (regulatory interactions) are added via various selection rules that are based on the structural and dynamical features of the 網絡 nodes (genes). Similar to well-studied models of 'explosive' 滲流, in our approach, links are selectively added so as to delay the transition to large-scale damage propagation, i.e. to make the 網絡 robust to small perturbations of gene states. We find that when selection depends only on structure, evolved 網絡s are resistant to widespread damage propagation, even without knowledge of individual gene propensities for becoming 'damaged'. We also observe that 網絡s evolved to avoid damage propagation tend towards disassortativity (i.e. directed links preferentially connect high degree 'source' genes to lo
※ 此為已發表論文，全文需透過期刊付費取得