本頁只刊出中文翻譯與中文說明；英文原文請見下方原文連結。
原文連結
論文資訊
- 類型：已發表論文
- 日期：2021-05-05
摘要
病毒es experience selective pressure on the timing and order of events during infection to maximize the number of viable offspring they produce. Additionally, they may experience variability in cellular environments encountered, as individual eukaryotic cells can display variation in gene expression among cells. This leads to a dynamic phenotypic landscape that 病毒es must face to replicate. To examine replication dynamics displayed by 病毒es faced with this variable landscape, we have developed a method for fitting a 隨機 mechanistic model of viral infection to time-lapse imaging data from high-throughput single-cell polio病毒 infection experiments. The model’s mechanistic parameters provide estimates of several aspects associated with the 病毒’s intracellular dynamics. We examine distributions of pa
※ 此為已發表論文，全文需透過期刊付費取得