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原文連結
論文資訊
- 類型：已發表論文
- 日期：2021-05-14
摘要
Atmospheric oxygen is thought to have played a vital role in the 演化 of large, complex multicellular organisms. Challenging the prevailing theory, we show that the transition from an anaerobic to an aerobic world can strongly suppress the 演化 of macroscopic multicellularity. Here we select for increased size in multicellular ‘snowflake’ yeast across a range of metabolically-available O2 levels. While yeast under anaerobic and high-O2 conditions evolved to be considerably larger, intermediate O2 constrained the 演化 of large size. Through sequencing and synthetic strain construction, we confirm that this is due to O2-mediated divergent selection acting on organism size. We show via 數學 modeling that our results stem from nearly universal 演化ary and biophysical trade-offs, and thus should apply br
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