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論文資訊
- 類型:已發表論文
- 日期:2021-06-10
摘要
Background Colorectal 癌症 (CRC) is a heterogeneous 癌症. Its treatment depends on its anatomical site and distinguishes between colon, rectum, and rectosigmoid junction 癌症. This study aimed to identify diagnostic and prognostic biomarkers using 網絡s of CRC-associated transcripts that can be built based on competing endogenous RNAs (ceRNA). Methods RNA expression and clinical 資訊 data of patients with colon, rectum, and rectosigmoid junction 癌症 were obtained from The 癌症 基因組 Atlas (TCGA). The RNA expression profiles were assessed through bioinformatics analysis, and a ceRNA was constructed for each CRC site. A functional enrichment analysis was performed to assess the functional roles of the ceRNA 網絡s in the prognosis of colon, rectum, and rectosigmoid junction 癌症. Finally, to verify the ceRNA im
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