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原文連結
論文資訊
- 類型：已發表論文
- 日期：2021-06-13
摘要
Understanding the relationship between the 大腦’s structural anatomy and 神經 activity is essential in identifying the structural therapeutic targets linked to the functional changes seen in neurological 疾病s. An implicit challenge is that the varying maps of the 大腦, or atlases, used across the neuroscience literature to describe the different regions of the 大腦 alters the hypotheses and predictions we make about the 大腦’s function of those regions. Here we demonstrate how parcellation scale, shape, and anatomical coverage of these atlases impact 網絡 topology, structure-function correlation (SFC), and the hypotheses we make about epilepsy 疾病 biology. Through the lens of our 疾病 system, we propose a general framework to evaluate the validity of an atlas used in an experimental system. This framework
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