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原文連結
論文資訊
- 類型：已發表論文
- 日期：2021-06-30
摘要
病毒es lie in a continuum between generalism and specialism depending on their ability to infect more or less hosts. While generalists are able to successfully infect a wide variety of hosts, specialists are limited to one or a few. Even though generalists seem to gain an advantage due to their wide host range, they usually pay a pleiotropic fitness cost within each host. On the contrary, a specialist has maximal fitness within its own host. A relevant yet poorly explored question is whether 病毒es differ in the way they interact with their hosts’ gene expression depending on their degree of specialization. Using a 基因組-wide association study approach, we have identified host genes whose expression depends on whether hosts were infected with more or less specialized viral strains. Four hundred
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