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原文連結
論文資訊
- 類型：已發表論文
- 日期：2021-07-12
摘要
Can evolvability itself be the product of adaptive 演化? To answer this question is challenging, because any DNA 突變 that alters only evolvability is subject to indirect, "second order" selection on the future effects of this 突變. Such indirect selection is weaker than "first-order" selection on 突變s that alter fitness, in the sense that it can operate only under restrictive conditions. Here I discuss a route to adaptive evolvability that overcomes this challenge. Specifically, a recent 演化 experiment showed that some 突變s can enhance both fitness and evolvability through a combination of direct and indirect selection. Unrelated evidence from gene duplication and the 演化 of gene regulation suggests that 突變s with such dual effects may not be rare. Through such 突變s, evolvability may increase at leas
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