本頁只刊出中文翻譯與中文說明；英文原文請見下方原文連結。
原文連結
論文資訊
- 類型：已發表論文
- 日期：2021-07-20
摘要
Complex dynamical fluctuations, from intracellular noise, 大腦 dynamics or computer traffic display bursting dynamics consistent with a critical state between order and disorder. Living close to the critical point has adaptive advantages and it has been conjectured that 演化 could select these critical states. Is this the case of living cells? A system can poise itself close to the critical point by means of the so-called self-organized 臨界性 (SOC). In this paper we present an engineered gene 網絡 displaying SOC behaviour. This is achieved by exploiting the saturation of the proteolytic degradation machinery in E. coli cells by means of a negative feedback loop that reduces congestion. Our critical motif is built from a two-gene circuit, where SOC can be successfully implemented. The potential imp
※ 此為已發表論文，全文需透過期刊付費取得