摘要 Chromosome 22q11.2 deletion syndrome (22q11.2DS)

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原文連結

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論文資訊

• 類型：已發表論文
• 日期：2021-10-22

摘要

Chromosome 22q11.2 deletion syndrome (22q11.2DS) is a multisystem disorder associated with multiple congenital anomalies, variable medical features, and neurodevelopmental differences resulting in diverse psychiatric phenotypes, including marked deficits in facial memory and 社會 cognition. Neuroimaging in individuals with 22q11.2DS has revealed differences relative to matched controls in BOLD fMRI activation during facial affect processing tasks. However, time-varying interactions between 大腦 areas during facial affect processing have not yet been studied with BOLD fMRI in 22q11.2DS. We applied constrained principal component analysis to identify temporally overlapping 大腦 activation patterns from BOLD fMRI data acquired during an emotion identification task from 58 individuals with 22q11.2DS

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