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原文連結
論文資訊
- 類型：已發表論文
- 日期：2021-11-17
摘要
Living systems break detailed balance at small scales, consuming energy and producing 熵 in the environment to perform molecular and cellular functions. However, it remains unclear how broken detailed balance manifests at macroscopic scales and how such dynamics support higher-order 生物 functions. Here we present a framework to quantify broken detailed balance by measuring 熵 production in macroscopic systems. We apply our method to the human 大腦, an organ whose immense metabolic consumption drives a diverse range of 認知 functions. Using whole-大腦 imaging data, we demonstrate that the 大腦 nearly obeys detailed balance when at rest, but strongly breaks detailed balance when performing physically and 認知ly demanding tasks. Using a dynamic Ising模型, we show that these large-scale violations of detaile
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