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原文連結
論文資訊
- 類型：已發表論文
- 日期：2022-04-28
摘要
網絡 control theory provides a framework by which neurophysiological dynamics of the 大腦 can be modelled as a function of the structural connectome constructed from 擴散 MRI. Average controllability describes the ability of a region to drive the 大腦 to easy-to-reach neurophysiological states whilst modal controllability describes the ability of a region to drive the 大腦 to difficult-to-reach states. In this study, we identify increases in mean average and modal controllability in children with drug-resistant epilepsy compared to healthy controls. Using simulations, we purport that these changes may be a result of increased thalamocortical connectivity. At the node level, we demonstrate decreased modal controllability in the thalamus and posterior cingulate regions. In those undergoing resective s
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