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論文資訊
- 類型：已發表論文
- 日期：2022-08-03
摘要
Aims 細菌l response to temperature changes can influence their pathogenicity to plants and humans. Changes in temperature can affect cellular and physiological responses in 細菌 that can in turn affect the 演化 and prevalence of 抗生素-resistance genes. Yet, how 抗生素-resistance genes influence microbial temperature response is poorly understood. Methods and Results We examined growth rates and physiological responses to temperature in two 物種—E. coli and Staph. epidermidis—after evolved resistance to 13 抗生素s. We found that evolved resistance results in 物種-, strain- and 抗生素-specific shifts in optimal temperature. When E. coli evolves resistance to nucleic acid and cell wall inhibitors, their optimal growth temperature decreases, and when Staph. epidermidis and E. coli evolve resistance to 蛋白質 synthesi
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