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原文連結
論文資訊
- 類型:已發表論文
- 日期:2022-10-20
摘要
We know much about pathogen 演化 and the 湧現 of new 疾病 strains, but less about host resistance and how it is signaled to other individuals and subsequently maintained. The clinein frequency of black-coated wolves (Canis lupus) across North America is hypothesized to result from a relationship with canine distemper 病毒 (CDV) outbreaks. We tested this hypothesis using cross- sectional data from wolf 族群s across North America that vary in the prevalence of CDVand the allele that makes coats black, longitudinal data from Yellowstone National Park, and modeling. We found that the frequency of CDV outbreaks generates fluctuating selection that results in heterozygote advantage that in turn affects the frequency of the black allele, optimal mating behavior, and black wolf cline across the continent.
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