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原文連結
論文資訊
- 類型：已發表論文
- 日期：2023-10-16
摘要
細菌 commonly adhere to surfaces where they compete for both space and resources. Despite the importance of surface growth, it remains largely elusive how 細菌 evolve on surfaces. We previously performed an 演化 experiment where we evolved distinct Bacilli 族群s under a selective regime that favored colony spreading. In just a few weeks, colonies of Bacillus subtilis showed strongly advanced expansion rates, increasing their radius 2.5-fold relative to that of the ancestor. Here, we investigate what drives their rapid 演化 by performing a uniquely detailed analysis of the 演化ary changes in colony development. We find 突變s in diverse global regulators, RicT, RNAse Y, and LexA, with strikingly similar pleiotropic effects: They lower the rate of sporulation and simultaneously facilitate colony expansion
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