本頁只刊出中文翻譯與中文說明；英文原文請見下方原文連結。
原文連結
論文資訊
- 類型：已發表論文
- 日期：2023-11-01
摘要
A hyperdiverse class of pathogens of humans and wildlife, including the malaria parasite Plasmodium falciparum, relies on multigene families to encode antigenic variation. As a result, high (asymptomatic) prevalence is observed despite high immunity in local 族群s under high-傳播 settings. The vast 多樣性 of "strains" and genes encoding this variation challenges the application of established models for the 族群 dynamics of such infectious 疾病s. 智能體-based models have been formulated to address theory on strain coexistence and structure, but their complexity can limit application to gain insights into 族群 dynamics. Motivated by P. falciparum malaria, we develop an alternative formulation in the form of a structured susceptible-infected-susceptible 族群 model in continuous time, where individuals are cla
※ 此為已發表論文，全文需透過期刊付費取得