聖塔非研究所

分子檢測對旅行者篩檢有效性的根本限制

2025 · 已發表論文 · 更新 2026/08/30 下午12:48

摘要 Despite the appeal of screening travellers to prevent case importation during infectious 疾病 outbreaks, evidence shows that symptom screening is largely ineffective in delaying the geograp…

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論文資訊

  • 類型:已發表論文
  • 日期:2025

摘要

Despite the appeal of screening travellers to prevent case importation during infectious 疾病 outbreaks, evidence shows that symptom screening is largely ineffective in delaying the geographical spread of infection. Molecular tests offer high sensitivity and specificity and can detect infections earlier than symptom screening, suggesting potential for improved outcomes. However, they were used to screen travellers for COVID-19 with mixed success. To investigate molecular screening's role in controlling COVID-19, and to quantify the effectiveness of screening for future pathogens of concern, we developed a probabilistic model that incorporates within-host viral kinetics. We then evaluated the potential effectiveness of screening travellers for influenza A, SARS-CoV-1, SARS-CoV-2, and Ebola 病毒

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