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原文連結
論文資訊
- 類型：已發表論文
- 日期：2025-01-09
摘要
Estimating the durability of immunity from 疫苗接種 is complicated by unreported re疫苗接種 and unobserved natural infection or reexposure, which could result in overestimation of protection longevity. We tested serial, cross-sectional serum samples from 2005 to 2015 (n = 2530) for immunoglobulin G (IgG) to examine measles seroprevalence, spatiotemporal patterns of titers across regions, and antibody dynamics among children aged 1-9 years who grew up during varying measles circulation in Madagascar under a 1-dose 疫苗接種 schedule. We found that measles seroprevalence generally decreased over this period. Furthermore, we conducted 2 nested serological surveys, analyzing 393 samples taken in 2005 (n = 158), a time point preceded by high levels of measles circulation, and 2015 (n = 235), a time point pr
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