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原文連結
論文資訊
- 類型：已發表論文
- 日期：2025-04-28
摘要
Modern psychiatry faces challenges in translating neuro生物 insights into treatments for severe illnesses. The mid-20th century witnessed the rise of molecular mechanisms as pathophysiological and treatment models, with recent holistic proposals keeping this focus unaltered. In this perspective, we explore how psychiatry can utilize systems neuroscience to develop a vertically integrated understanding of 大腦 function to inform treatment. Using schizophrenia as a case study, we discuss scale-related challenges faced by researchers studying molecules, circuits, 網絡s, and cognition and clinicians operating within existing frameworks. We emphasize computation as a bridging 語言, with algorithmic models like hierarchical predictive processing offering explanatory potential for targeted interventions.
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