本頁只刊出中文翻譯與中文說明；英文原文請見下方原文連結。
原文連結
論文資訊
- 類型：已發表論文
- 日期：2025-09-22
摘要
Systemic lupus erythematosus (SLE) is a chronic auto免疫 疾病, with 認知 dysfunction being one of its most common neuropsychiatric manifestations. 認知 flexibility relies on the integration of 大腦 structure and function, with white matter 網絡s providing anatomical constraints for functional dynamics. Reduced 認知 flexibility is frequently observed in SLE, but the underlying structure-function integration changes remain poorly understood. This study investigated whether 大腦 structure-function integration is altered in SLE and how it links to 認知 flexibility. We examined 22 SLE patients without clinically overt neuropsychiatric manifestation (age: 34.99 +/- 10.67; 18 females) and 60 healthy controls (HCs) (age: 28.43 +/- 8.56; 29 females). Using 擴散 MRI and task-based fMRI acquired during the Montreal Card
※ 此為已發表論文，全文需透過期刊付費取得