本頁只刊出中文翻譯與中文說明；英文原文請見下方原文連結。
原文連結
論文資訊
- 類型：工作論文
- 編號：工作論文 #690
- 日期：2026-03-18
摘要
Dominance is a form of phenotypic robustness to mutations. Understanding how such robustness can evolve provides a window on how the relation between genotype and phenotype can change during evolution.在群體對基因中，試圖解釋遺傳率的影響性或突變性的初始頻率。 Given such requirements, dominance is unlikely to evolve in most cases.在本文中，我們提出了一個整合酶動力學、遺傳學和群體動力學的理論模型，以解決代謝生理學中的優勢進化問題。考慮到米氏型酶催化的機制限制，我們表明優勢可以透過對雜合子頻率和/或突變率不敏感的選擇機制來進化。 This is due to the prevalence of alleles that have direct fitness effects in addition to dominance modification effects. Dominance can evolve as an incidental side effect of selection for such dual-effect alleles.